Suffering from pain is the primary reason, why patients
(human/non-human) visit hospital. Pain is described as an unpleasant
sensory and emotional experience associated with actual or
potential tissue damage, or is described in terms of such damage (IASP,
1979). Pain is a source of a big economic loss due to inability to
work and cost of medical care.
Our research is aimed at providing insights into pain mechanisms
(reception, pathogenesis and regulation) which will ultimately
contribute to the alleviation of suffering of patients. Over the years
the research group has developed pain models based on our wild fauna.
Thus a comparative analysis of nociceptive and anti-nociceptive
mechanisms has been performed in wild rodents (naked and root rat mole
rats), crocodiles, tortoises and terrapins. These researches have
yielded invaluable information, which is useful for reference material
for use by veterinarians, zoo keepers, pet owners and persons farming
these animals, and those studying evolution.
The second major area of our research is validation/investigations
on the analgesic and anti-inflammatory properties of herbs/plants used
by Traditional Medical Practitioners for the management of pain, and
that due to rheumatoid and osteoarthritis. The discovery of the active
principles in these plants and their mode of action is a key area of